Donald Trump said something rude to Meryl Streep, leading Rosie O’Donnell to respond in kind on Twitter

Photo by: Demis Maryannakis/STAR MAX/IPx 5/9/16 Rosie O'Donnell at The SAG-AFTRA Foundation Conversations. (NYC) FILE - In this May 6, 2016 file photo, Republican presidential candidate Donald Trump speaks during a rally in Eugene, Ore. The city of Eugene plans to bill the Donald Trump campaign nearly $100,000 to pay for costs associated with last month's visit. Police Chief Pete Kerns said in an email Wednesday, June 22, 2016, that overtime compensation for police officers totaled $78,000 while firefighters and other city employees racked up another $10,000 in OT. (AP Photo/Ted S. Warren, File)

In yet another episode of Donald & Rosie, the comedian exchanged words with the president-elect on Monday afternoon.

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RELATED: Rosie O’Donnell starts off the new year by calling Trump “mentally unstable”

On Sunday, actress Meryl Streep criticized Trump’s behavior, including his mocking of a disabled reporter, while accepting a Golden Globe Award.

Trump shot back angrily in a series of tweets:

https://twitter.com/realDonaldTrump/status/818419002548568064

In the first, he called her “one of the most over-rated actresses in Hollywood.” He also accused her of being a “Hillary flunky.”

RELATED: Rosie O’Donnell casts doubt on Trump’s intelligence in typo-laden tweet

O’Donnell jumped in, telling Trump how she really felt about him:

She sent:

@realDonaldTrump – the worlds best actress spoke the truth about you – the world worst human and biggest liar

Trump has yet to respond as of this writing.

That said, Trump has also taken his fair share of shots.

What do you think?

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Things got pretty steamy when Jessica Biel and Ellen DeGeneres decided to prank Justin Timberlake on “Ellen”