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Senators Rand Paul (R-Ky.), Cory Booker (D-NJ) and Kirsten Gillibrand (D-NY) plan to introduce what advocates are calling a first of its kind bill on Tuesday, that would end the federal ban on medical marijuana.

In a joint statement, the senators touted the “new bipartisan legislation to allow patients, doctors and businesses in states that have already passed medical marijuana laws to participate in those programs without fear of federal prosecution.”

Dan Riffle, director of federal policies for the Marijuana Policy Project, told The Washington Post, “This is a significant step forward when it comes to reforming marijuana laws at the federal level.” “The vast majority of Americans support laws that allow seriously ill people to access medical marijuana,” he added.

Michael Collins, a policy manager for The Drug Policy Alliance, said in a statement “Almost half the states have legalized marijuana for medical use; it’s long past time to end the federal ban.” Collins added, “This bipartisan legislation allows states to set their own medical marijuana policies and ends the criminalization of patients, their families, and the caregivers and dispensary owners and employees who provide them their medicine.”

According to The Drug Policy Alliance:

Twenty-three states and the District of Columbia have laws that legalize and regulate marijuana for medicinal purposes. Twelve more states have laws on the books or are about to be signed into law by their governors regulating cannabidiol (CBD) oils, a non-psychotropic component of medical marijuana which some parents are utilizing to treat their children’s seizures. Four states and the District of Columbia have legalized marijuana for non-medical use.

Many polls show that more Americans than ever increasingly support legal marijuana for medical and ever recreational use.

The senators will make their announcement at 12:30 Tuesday ET.